Holmes is a little too scientific for my tastes — it approaches to cold-bloodedness. I could imagine his giving a friend a little pinch of the latest vegetable alkaloid, not out of malevolence, you understand, but simply out of a spirit of inquiry in order to have an accurate idea of the effects. To do him justice, I think that he would take it himself with the same readiness. He appears to have a passion for definite and exact knowledge.

I owe my success to having listened respectfully to the very best advice, and then going away and doing the exact opposite.

Life is not an exact science, it is an art

It is the nature of all greatness not to be exact.

Hindsight is an exact science.

It is also naïve empiricism to provide, in support of some argument, series of eloquent confirmatory quotes by dead authorities. By searching, you can always find someone who made a well-sounding statement that confirms your point of view — and, on every topic, it is possible to find another dead thinker who said the exact opposite.